03 AUG 2025

Sildenafil Tablets: Uses, Effectiveness, and Safety Overview

Dr. Rahul Menon

Pharma Analyst

Sildenafil is one of the most prescribed drugs for erectile dysfunction (ED) and pulmonary arterial hypertension (PAH). It enhances blood flow to specific tissues by relaxing smooth muscle in blood vessels.

        Quick Fact: Sildenafil was initially studied for heart problems before researchers discovered its potential for improving erectile function.
      

🧠 Mechanism of Action

Sildenafil inhibits PDE5 enzymes, allowing cyclic GMP to accumulate and promote smooth muscle relaxation. This results in improved blood circulation in target areas.

💊 Recommended Dosage

Typical doses range from **25 mg to 100 mg**, taken 30–60 minutes before sexual activity. Effects can last up to 4 hours depending on individual metabolism.

⚠️ Side Effects and Precautions

Headache and flushing
Upset stomach
Visual disturbances (blue tint)
Rarely: prolonged erection (priapism)

Avoid combining with nitrates or heavy alcohol consumption. Consult a doctor if you experience chest pain or heart issues.

✅ Summary

Sildenafil remains a reliable choice for men with ED when used responsibly. Always follow medical advice and avoid self-medication.

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